WebAutophagy is a crucial host-defense mechanism against Mycobacterium tuberculosis (Mtb) infection by spanning innate and adaptive immune functions. TRIM22 is a member of … WebThe effect of VAPB and PTPIP51 depletion on autophagic flux was directly ascribed to the loosening of ER-mitochondria contacts and to the consequent decreased ER to …
FOXO3/TRIM22 axis abated the antitumor effect of gemcitabine in …
WebOct 1, 2024 · Free Online Library: The E3 Ligases in Cervical Cancer and Endometrial Cancer. by "Cancers"; Health, general Endometrial cancer Health aspects Mortality Canada Ubiquitin WebIdentification of Crucial Genes and Pathways Associated with Atherosclerotic Plaque in Diabetic Patients get new health card online
TRIMs for Autophagy Science Signaling
Inflammasomes are protein complexes formed by (1) sensor/scaffold proteins (e.g., NLRP1, NLRP3, AIM2, NLRC4, and Pyrin/TRIM20), (2) the adaptor ASC (also known as PYCARD), (3) the procaspase 1. Inflammasome activation is triggered by a wide range of pathogen-associated or danger-associated molecular … See more TRIM proteins were reported to regulate both positively and negatively the activity of various components of the cGAS/STING pathway by modulating either protein … See more In addition to the STING pathway, TRIM proteins are involved in the autophagy regulation of other NF-κB-regulated pathways to avoid an excessive or prolonged … See more An important autophagic contribution of TRIM proteins to the innate immune response is definitely their ability to directly bind pathogens’ structures and deliver … See more In addition to the important autophagic roles played in the immune response, TRIMs act as autophagy receptors in response to other critical cellular stresses. For … See more WebJul 1, 2024 · Autophagy activation was found in OS cells which were overexpressed TRIM22, thus leading to autophagic cell death. Treatment with N-Acetylcysteine (NAC), a ROS … WebSep 12, 2024 · The autophagic pathways can be distinguished as the canonical or the selective autophagic pathway. The selective autophagy receptors deliver cargoes to the autophagosomes for selective degradation . It has been shown that ULK1/2, FIP200 and ATG13 are critical for initiation of the classical autophagic pathway . christmas tags printable from santa