Webb10 sep. 2024 · Sticking is one of the most common problems tablet manufacturers encounter. Sticking describes the buildup of granules on the punch-tip face, which can be caused by several factors, including the formulation’s physicochemical properties and the surface characteristics of the punch face. Because sticking is such a universal problem … Webb13 mars 2024 · Good tablet design is extremely important; it has an impact upon anti-counterfeiting, tooling strength, tablet coating, durability and functionality. It also helps to avoid downstream manufacturing problems such as tablet sticking, picking, lamination, capping and premature tooling failures. Several elements need to be considered when …
TABLETING PROBLEMS - CAUSES AND REMEDIES - GMP Journal
Webb2 okt. 2013 · Tablet sticking, in which material adheres to the surface of a tablet-punch face, is an ongoing and costly problem in pharmaceutical manufacturing and is a significant issue for drug-product formulators. Analytical methods can be used to troubleshoot sticking problems and develop screening methods. Webb1 juni 2010 · ‘Picking’ and ‘sticking’ are often used to mean the same thing, but are actually different defects. ‘Picking’ can be described as compressed material that has adhered to detail on the punch face, resulting in ‘picking out’ parts of the tablet face. This can usually be resolved by re-designing the embossing on the tablet. i and love and you dry cat food reviews
Pharmaceutical Technology-II MCQs with Answers (Part:- 2)
Webb8 maj 2024 · • Picking is the case of sticking involves adhering of some portion of coated layer to pan or to another tablet at the point of contact. 8-May-18 NIPER Ahmedabad 12 Causes Remedies • Higher rate of application of coating solution • Inefficient drying. Use optimum and efficient drying conditions. Increase the inlet air temperature. Decrease the … Webb21 apr. 2024 · [solution]: press the tablet in time or take corresponding moisture-proof measures (such as sealing particles with tape). 11. The punch has curl or crack or too deep concavity, which is easy to cause stick punch. [solution]: correct or replace the punch. 12. The raw material itself (such as moisture) causes sticking and flushing. Webb8 aug. 2024 · Picking is a specific type of sticking in which particles stick within the letters andlogos thatareembossedordebossed on the facesof thecompression tooling.SeeFigure 2. Regardlesswhetherit’ssticking orpicking, the resultis a defective tablet. To salvage the batch, you may have to visually inspect the tablets. i and love and you ingredients