Modified mosher method
Web31 aug. 1997 · @article{Xiao1997StudyFT, title={Study for the determination of the absolute configuration of fluoromethylated secondary alcohols by the modified Mosher method}, author={Ling Xiao and Takashi Yamazaki and Tomoya Kitazume and Tetsu Yonezawa and Yoshitaka Sakamoto and Kouji Nogawa}, journal={Journal of Fluorine Chemistry}, … Web12 dec. 2005 · However, the modified Mosher method is well known to give an absolute configuration for a chiral carbon atom with a hydroxyl group (12, 13). Luminamicin has …
Modified mosher method
Did you know?
Web10 sep. 2024 · Application of Mosher’s method for absolute configuration assignment to bioactive plants and fungi metabolites Dedicated to Carlo Bertucci on the occasion of his retirement and as acknowledgment of his significant contribution to understanding the role of chiral recognition in pharmaceutical science. Alessio Cimmino a , Marco Masi a , WebFour undescribed phenolic compounds, namely asperpropanols A–D (1–4), along with two known congeners 5 and 6, were isolated from Aspergillus puniceus A2, a deep-sea-derived fungus. The gross structures of the compounds were established by detailed analyses of the HRESIMS and NMR data, and their absolute configurations were resolved by modified …
Web18 jan. 2024 · The only remained question was the absolute configuration of C-13 for 3 and clonostachydiol, which was also deduced by application of the modified Mosher’s method for the diol fragments 8 and 9 ... Web11 feb. 2015 · A modified Mosher method was used to determine the configuration of the C-2′ asymmetric center [ 7 ]. Esterification of 2 by ( R )- and ( S )-MTPA acid chlorides at the C-2′ hydroxyl formed the ( S )- and ( R )-MTPA esters 2a and 2b, respectively.
Web31 okt. 2006 · This article describes the application of the modified Mosher’s method to a variety of natural products possessing a secondary alcohol for determining their absolute … Web4 okt. 2007 · Mosher ester (and amide) analysis, especially the modified version, is remarkably powerful and general. The most complementary alternative, predicated on the same concepts, is the use of O...
WebThe absolute configurations of some hydroxy-fatty acids were examined by the modified Mosher's method proposed by Ohtani et al. The absolute configurations of the major components were determined from NMR data of their ΜΤΡΑ esters and 2-ΝΜΑ esters. The application of Mosher's method for the anti-gly …
Web4 jul. 2006 · DOI: 10.1246/BCSJ.79.965 Corpus ID: 95559137; The Modified Mosher’s Method and the Sulfoximine Method @article{Kusumi2006TheMM, title={The Modified Mosher’s Method and the Sulfoximine Method}, author={Takenori Kusumi and Takashi Ooi and Yumi Ohkubo and Tetsuya Yabuuchi}, journal={Bulletin of the Chemical Society of … high westwoodWeb10 sep. 2024 · The review deals with the application of the NMR advanced Mosher's method for the assignment of the absolute configuration to plant and fungal metabolites … high westland terrierWeb19 feb. 2024 · The absolute configuration was confirmed by the modified Mosher method . The hydroxy group was protected as a MOM ether and both of silyl protecting group were removed to give 11. Then the less hindered terminal hydroxy group was selectively protected as a TBS ether and another was oxidized to aldehyde 12 in 73% yield. small in norwegianWeb15 nov. 2010 · The crystal structure (CCDC-780372) fully confirmed the constitution of the pentacyclic ring system and the relative configuration of 1 (Fig. 2).To establish the absolute configuration of 1, the modified Mosher method was applied. 15 Through analysis of the specific 1 H NMR shifts (Fig. 3 and Table S2) we were able to determine the absolute … high westwood consettWeb13 aug. 2013 · The modified Mosher method, using MTPA derivatization ( 9 and 10 ), established the absolute configuration of 3 as 4 R, 5 R, 12 S, and 13 R ( Figure 2 ). Table 2. NMR data for 3 and 4 in pyridine- d5 . high westwood newcastleWeb28 feb. 2024 · The structures of all new compounds were determined by spectroscopic data, and the absolute configurations of compounds 1, 2, 13, 16, and 26 were determined by … high westwood camp siteWeb23 apr. 2010 · Furthermore, the absolute stereochemistry of pentacecilides was determined by using the modified Mosher method 10 for pentacecilide C. Figure 1 Structures of pentacecilides A–D. small in law home plans