WebMay 21, 2024 · Mass spectrometry as an orthogonal method for HCP analysis is very powerful. Mainly because it provides detailed information about the specific HCPs – … WebSep 17, 2024 · Presence of host cell protein (HCP) contaminants in the final product, even at very low levels, may elicit unpredictable and serious immunogenic response in humans. The accurate detection, identification and quantification of HCPs during biotherapeutic development is thus critical in ensuring patient safety, and is a regulatory requirement.
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