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Web6 lug 2024 · Notably, MMβA-mono occupies a wider region of the catalytic cavity, interacting with residues Val78, Asp94, Ser112, Tyr114, Thr115, Glu167, and Arg170, relative to previously developed small ... Web4 dic 2024 · In 4 unrelated girls with autosomal dominant intellectual developmental disorder-60 with seizures (MRD60; 618587), Helbig et al. (2024) identified a de novo … exd mb iict6 gb
NM_022836.4(DCLRE1B):c.508C>T (p.Arg170Ter) AND multiple …
Web25 giu 2015 · Thrombin is a serine protease of the chymotrypsin family that acts both as a procoagulant and as an anticoagulant by cleaving either factor VIII, factor V and fibrinogen or protein C, respectively. Numerous previous studies have shown that electropositive regions at a distance from the active site, so called exosites, are of major importance for … Web26 ago 2024 · This sequence change creates a premature translational stop signal (p.Arg170*) in the DCLRE1B gene. While this is not anticipated to result in nonsense … WebThe amino acid residues Asp106, Asp287, Tyr255, Arg170 and Glu514 have been identified to play catalytically important role in substrate binding. Docking and interaction of … exd-sh1 controller manual